Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

BACKGROUND: Targeted genomic enrichment (TGE) is a widely used method for isolating and enriching specific genomic regions prior to massively parallel sequencing. To make effective use of sequencer output, barcoding and sample pooling (multiplexing) after TGE and prior to sequencing (post-capture mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shearer, A Eliot, Hildebrand, Michael S, Ravi, Harini, Joshi, Swati, Guiffre, Angelica C, Novak, Barbara, Happe, Scott, LeProust, Emily M, Smith, Richard JH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534602/
https://www.ncbi.nlm.nih.gov/pubmed/23148716
http://dx.doi.org/10.1186/1471-2164-13-618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534602/
https://www.ncbi.nlm.nih.gov/pubmed/23148716
http://dx.doi.org/10.1186/1471-2164-13-618

Ejemplares similares