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Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment
BACKGROUND: Targeted genomic enrichment (TGE) is a widely used method for isolating and enriching specific genomic regions prior to massively parallel sequencing. To make effective use of sequencer output, barcoding and sample pooling (multiplexing) after TGE and prior to sequencing (post-capture mu...
Autores principales: | Shearer, A Eliot, Hildebrand, Michael S, Ravi, Harini, Joshi, Swati, Guiffre, Angelica C, Novak, Barbara, Happe, Scott, LeProust, Emily M, Smith, Richard JH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534602/ https://www.ncbi.nlm.nih.gov/pubmed/23148716 http://dx.doi.org/10.1186/1471-2164-13-618 |
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