Reconstructing DNA copy number by joint segmentation of multiple sequences

BACKGROUND: Variations in DNA copy number carry information on the modalities of genome evolution and mis-regulation of DNA replication in cancer cells. Their study can help localize tumor suppressor genes, distinguish different populations of cancerous cells, and identify genomic variations respons...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhongyang, Lange, Kenneth, Sabatti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534631/
https://www.ncbi.nlm.nih.gov/pubmed/22897923
http://dx.doi.org/10.1186/1471-2105-13-205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534631/
https://www.ncbi.nlm.nih.gov/pubmed/22897923
http://dx.doi.org/10.1186/1471-2105-13-205

Ejemplares similares