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HIV-1 Tat Promotes Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) vIL-6-Induced Angiogenesis and Tumorigenesis by Regulating PI3K/PTEN/AKT/GSK-3β Signaling Pathway

Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is etiologically associated with KS, the most common AIDS-related malignancy. KS is characterized by vast angiogenesis and hyperproliferative spindle cells. We have previously reported that HIV-1 Tat can trigger KSHV reactivation and accelerate Kap...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Xue, Min, Qin, Di, Zhu, Xiaofei, Wang, Cong, Zhu, Jianzhong, Hao, Tingting, Cheng, Lin, Chen, Xiuying, Bai, Zhiqiang, Feng, Ninghan, Gao, Shou-Jiang, Lu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534639/
https://www.ncbi.nlm.nih.gov/pubmed/23301033
http://dx.doi.org/10.1371/journal.pone.0053145