Cargando…

Old Players with a Newly Defined Function: Fra-1 and c-Fos Support Growth of Human Malignant Breast Tumors by Activating Membrane Biogenesis at the Cytoplasm

A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells demand high rates of phospholipid synthesis required for membrane biogenesis to support their growth. c-Fos, in addition to its AP-1 transcription factor activity, is the only protein known up to date that...

Descripción completa

Detalles Bibliográficos
Autores principales: Motrich, Ruben D., Castro, Gonzalo M., Caputto, Beatriz L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534677/
https://www.ncbi.nlm.nih.gov/pubmed/23301044
http://dx.doi.org/10.1371/journal.pone.0053211