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Neutralization of TSLP Inhibits Airway Remodeling in a Murine Model of Allergic Asthma Induced by Chronic Exposure to House Dust Mite

Chronic allergic asthma is characterized by Th2-typed inflammation, and contributes to airway remodeling and the deterioration of lung function. However, the initiating factor that links airway inflammation to remodeling is unknown. Thymic stromal lymphopoietin (TSLP), an epithelium-derived cytokine...

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Detalles Bibliográficos
Autores principales: Chen, Zhuang-Gui, Zhang, Tian-Tuo, Li, Hong-Tao, Chen, Fen-Hua, Zou, Xiao-Ling, Ji, Jing-Zhi, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534685/
https://www.ncbi.nlm.nih.gov/pubmed/23300949
http://dx.doi.org/10.1371/journal.pone.0051268