Epstein–Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis

Epstein–Barr virus-induced gene 3 (EBI3) associates with p28 and p35 to form the immunomodulatory cytokines IL-27 and IL-35, respectively. Infection of EBI3 −/− mice with the neuroadapted JHM strain of mouse hepatitis virus (JHMV) resulted in increased mortality that was not associated with impaired...

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Detalles Bibliográficos
Autores principales: Tirotta, Emanuele, Duncker, Patrick, Oak, Jean, Klaus, Suzi, Tsukamoto, Michelle R., Gov, Lanny, Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534940/
https://www.ncbi.nlm.nih.gov/pubmed/23102608
http://dx.doi.org/10.1016/j.jneuroim.2012.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534940/
https://www.ncbi.nlm.nih.gov/pubmed/23102608
http://dx.doi.org/10.1016/j.jneuroim.2012.10.005

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