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Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21

Three predisposition genes have been identified for cutaneous malignant melanoma (CMM), but they account for only about 25% of melanoma clusters/pedigrees. Linkage analyses of melanoma pedigrees from many countries have failed to identify significant linkage evidence for the remaining predisposition...

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Detalles Bibliográficos
Autores principales: Cannon-Albright, Lisa A, Teerlink, Craig C, Farnham, James M, Thomas, Alun, Zone, John J, Leachman, Sancy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535071/
https://www.ncbi.nlm.nih.gov/pubmed/22951724
http://dx.doi.org/10.1038/jid.2012.271