Cargando…

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

Selective translation of survival proteins is an important facet of the cellular stress response. We recently demonstrated that this translational control involves a stress-specific reprogramming of modified ribonucleosides in tRNA. Here we report the discovery of a step-wise translational control m...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Clement T.Y., Pang, Yan Ling Joy, Deng, Wenjun, Babu, I. Ramesh, Dyavaiah, Madhu, Begley, Thomas J., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535174/
https://www.ncbi.nlm.nih.gov/pubmed/22760636
http://dx.doi.org/10.1038/ncomms1938