Identification of Two Novel NPM1 Mutations in Patients with Acute Myeloid Leukemia

BACKGROUND: Genetic abnormalities in adult AML are caused most frequently by somatic mutations in exon 12 of the NPM1 gene, which is observed in approximately 35% of AML patients and up to 60% of patients with cytogenetically normal AML (CN-AML). METHODS: We performed mutational analysis, including...

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Detalles Bibliográficos
Autores principales: Jeon, Yongbum, Seo, Sang Won, Park, Seonyang, Park, Seungman, Kim, So Yeon, Ra, Eun Kyung, Park, Sung Sup, Seong, Moon-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535198/
https://www.ncbi.nlm.nih.gov/pubmed/23301224
http://dx.doi.org/10.3343/alm.2013.33.1.60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535198/
https://www.ncbi.nlm.nih.gov/pubmed/23301224
http://dx.doi.org/10.3343/alm.2013.33.1.60

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