Multi-cell type human liver microtissues for hepatotoxicity testing

Current 2-dimensional hepatic model systems often fail to predict chemically induced hepatotoxicity due to the loss of a hepatocyte-specific phenotype in culture. For more predictive in vitro models, hepatocytes have to be maintained in a 3-dimensional environment that allows for polarization and ce...

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Detalles Bibliográficos
Autores principales: Messner, S., Agarkova, I., Moritz, W., Kelm, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535351/
https://www.ncbi.nlm.nih.gov/pubmed/23143619
http://dx.doi.org/10.1007/s00204-012-0968-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535351/
https://www.ncbi.nlm.nih.gov/pubmed/23143619
http://dx.doi.org/10.1007/s00204-012-0968-2

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