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Heme orientation modulates histidine dissociation and ligand binding kinetics in the hexacoordinated human neuroglobin
Neuroglobin (Ngb) is a globin present in the brain and retina of mammals. This hexacoordinated hemoprotein binds small diatomic molecules, albeit with lower affinity compared with other globins. Another distinctive feature of most mammalian Ngb is their ability to form an internal disulfide bridge t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535368/ https://www.ncbi.nlm.nih.gov/pubmed/23135388 http://dx.doi.org/10.1007/s00775-012-0956-2 |