Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity

A consistent clinical feature of amyotrophic lateral sclerosis (ALS) is the sparing of eye movements and the function of external sphincters, with corresponding preservation of motor neurons in the brainstem oculomotor nuclei, and of Onuf’s nucleus in the sacral spinal cord. Studying the differences...

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Detalles Bibliográficos
Autores principales: Brockington, Alice, Ning, Ke, Heath, Paul R., Wood, Elizabeth, Kirby, Janine, Fusi, Nicolò, Lawrence, Neil, Wharton, Stephen B., Ince, Paul G., Shaw, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535376/
https://www.ncbi.nlm.nih.gov/pubmed/23143228
http://dx.doi.org/10.1007/s00401-012-1058-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535376/
https://www.ncbi.nlm.nih.gov/pubmed/23143228
http://dx.doi.org/10.1007/s00401-012-1058-5

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