Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection

Ligand polyvalency is a powerful modulator of protein–receptor interactions. Host–pathogen infection interactions are often mediated by glycan ligand–protein interactions, yet its interrogation with very high copy number ligands has been limited to heterogenous systems. Here we report that through t...

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Detalles Bibliográficos
Autores principales: Ribeiro-Viana, Renato, Sánchez-Navarro, Macarena, Luczkowiak, Joanna, Koeppe, Julia R., Delgado, Rafael, Rojo, Javier, Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535419/
https://www.ncbi.nlm.nih.gov/pubmed/23250433
http://dx.doi.org/10.1038/ncomms2302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535419/
https://www.ncbi.nlm.nih.gov/pubmed/23250433
http://dx.doi.org/10.1038/ncomms2302

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