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TNF-α induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide

BACKGROUND: MAdCAM-1 is an adhesion molecule expressed in Peyer's patches and lymphoid tissues which is mobilized by cytokines like TNF-α and is a major determinant of lymphocyte trafficking to the gut in human inflammatory bowel disease (IBD). It has been suggested that both reactive oxygen an...

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Detalles Bibliográficos
Autores principales: Oshima, Tadayuki, Jordan, Paul, Grisham, Matthew B, Alexander, Jonathan S, Jennings, Merilyn, Sasaki, Makotoh, Manas, Kenneth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35355/
https://www.ncbi.nlm.nih.gov/pubmed/11481030
http://dx.doi.org/10.1186/1471-230X-1-5