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DFI: gene feature discovery in RNA-seq experiments from multiple sources

BACKGROUND: Differential expression detection for RNA-seq experiments is often biased by normalization algorithms due to their sensitivity to parametric assumptions on the gene count distributions, extreme values of gene expression, gene length and total number of sequence reads. RESULTS: To overcom...

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Detalles Bibliográficos
Autores principales: Ozer, Hatice Gulcin, Parvin, Jeffrey D, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535702/
https://www.ncbi.nlm.nih.gov/pubmed/23281963
http://dx.doi.org/10.1186/1471-2164-13-S8-S11