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Structurally similar estradiol analogs uniquely alter the regulation of intracellular signaling pathways

Ligand structure can affect the activation of nuclear receptors, such as estrogen receptors (ERs), and their control of signaling pathways for cellular responses including death and differentiation. We hypothesized that distinct biological functions of similar estradiol (E(2)) analogs could be ident...

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Detalles Bibliográficos
Autores principales: Yarger, James G, Babine, Robert E, Bittner, Michael, Shanle, Erin, Xu, Wei, Hershberger, Pamela, Nye, Steven H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Endocrinology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535725/
https://www.ncbi.nlm.nih.gov/pubmed/23132914
http://dx.doi.org/10.1530/JME-12-0083