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In Silico Docking of HNF-1a Receptor Ligands

Background. HNF-1a is a transcription factor that regulates glucose metabolism by expression in various tissues. Aim. To dock potential ligands of HNF-1a using docking software in silico. Methods. We performed in silico studies using HNF-1a protein 2GYP·pdb and the following softwares: ISIS/Draw 2.5...

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Detalles Bibliográficos
Autores principales: Sridhar, Gumpeny Ramachandra, Nageswara Rao, Padmanabhuni Venkata, Kaladhar, Dowluru SVGK, Devi, Tatavarthi Uma, Kumar, Sali Veeresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535823/
https://www.ncbi.nlm.nih.gov/pubmed/23316227
http://dx.doi.org/10.1155/2012/705435