Cortical synaptogenesis and excitatory synapse number are determined via a Neuroligin-1-dependent intercellular competition

Members of the neuroligin (NL) family of cell-adhesion proteins are found at excitatory and inhibitory synapses and are mutated in some familial forms of autism spectrum disorders. Although they display synaptogenic properties in heterologous systems, a function of NLs in vivo in regulating synapse...

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Detalles Bibliográficos
Autores principales: Kwon, Hyung-Bae, Kozorovitskiy, Yevgenia, Oh, Won-Jong, Peixoto, Rui T., Akhtar, Nazia, Saulnier, Jessica L., Gu, Chenghua, Sabatini, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536444/
https://www.ncbi.nlm.nih.gov/pubmed/23143522
http://dx.doi.org/10.1038/nn.3256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536444/
https://www.ncbi.nlm.nih.gov/pubmed/23143522
http://dx.doi.org/10.1038/nn.3256

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