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Cortical synaptogenesis and excitatory synapse number are determined via a Neuroligin-1-dependent intercellular competition
Members of the neuroligin (NL) family of cell-adhesion proteins are found at excitatory and inhibitory synapses and are mutated in some familial forms of autism spectrum disorders. Although they display synaptogenic properties in heterologous systems, a function of NLs in vivo in regulating synapse...
Autores principales: | Kwon, Hyung-Bae, Kozorovitskiy, Yevgenia, Oh, Won-Jong, Peixoto, Rui T., Akhtar, Nazia, Saulnier, Jessica L., Gu, Chenghua, Sabatini, Bernardo L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536444/ https://www.ncbi.nlm.nih.gov/pubmed/23143522 http://dx.doi.org/10.1038/nn.3256 |
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