Cargando…

Structure of the Mu transpososome illuminates evolution of DDE recombinases

Studies of bacteriophage Mu transposition paved the way for understanding retroviral integration and V(D)J recombination as well as many other DNA transposition reactions. Here we report the structure of Mu transposase (MuA) in complex with bacteriophage DNA ends and target DNA, determined from data...

Descripción completa

Detalles Bibliográficos
Autores principales: Montaño, Sherwin P., Pigli, Ying Z., Rice, Phoebe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536463/
https://www.ncbi.nlm.nih.gov/pubmed/23135398
http://dx.doi.org/10.1038/nature11602