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Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
Understanding the basis for differential responses to drug therapies remains a challenge despite advances in genetics and genomics. Induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to investigate the pharmacology of disease processes in therapeutically and genetically releva...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536519/ https://www.ncbi.nlm.nih.gov/pubmed/23277474 http://dx.doi.org/10.1085/jgp.201210899 |