Ablation of cardiac myosin–binding protein-C accelerates contractile kinetics in engineered cardiac tissue

Hypertrophic cardiomyopathy (HCM) caused by mutations in cardiac myosin–binding protein-C (cMyBP-C) is a heterogenous disease in which the phenotypic presentation is influenced by genetic, environmental, and developmental factors. Though mouse models have been used extensively to study the contracti...

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Detalles Bibliográficos
Autores principales: de Lange, Willem J., Grimes, Adrian C., Hegge, Laura F., Ralphe, J. Carter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536521/
https://www.ncbi.nlm.nih.gov/pubmed/23277475
http://dx.doi.org/10.1085/jgp.201210837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536521/
https://www.ncbi.nlm.nih.gov/pubmed/23277475
http://dx.doi.org/10.1085/jgp.201210837

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