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Ablation of cardiac myosin–binding protein-C accelerates contractile kinetics in engineered cardiac tissue

Hypertrophic cardiomyopathy (HCM) caused by mutations in cardiac myosin–binding protein-C (cMyBP-C) is a heterogenous disease in which the phenotypic presentation is influenced by genetic, environmental, and developmental factors. Though mouse models have been used extensively to study the contracti...

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Detalles Bibliográficos
Autores principales:	de Lange, Willem J., Grimes, Adrian C., Hegge, Laura F., Ralphe, J. Carter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536521/ https://www.ncbi.nlm.nih.gov/pubmed/23277475 http://dx.doi.org/10.1085/jgp.201210837

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