Aquaporin-4–dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation

Potassium (K(+)) ions released into brain extracellular space (ECS) during neuroexcitation are efficiently taken up by astrocytes. Deletion of astrocyte water channel aquaporin-4 (AQP4) in mice alters neuroexcitation by reducing ECS [K(+)] accumulation and slowing K(+) reuptake. These effects could...

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Detalles Bibliográficos
Autores principales: Jin, Byung-Ju, Zhang, Hua, Binder, Devin K., Verkman, A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536523/
https://www.ncbi.nlm.nih.gov/pubmed/23277478
http://dx.doi.org/10.1085/jgp.201210883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536523/
https://www.ncbi.nlm.nih.gov/pubmed/23277478
http://dx.doi.org/10.1085/jgp.201210883

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