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Aquaporin-4–dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation
Potassium (K(+)) ions released into brain extracellular space (ECS) during neuroexcitation are efficiently taken up by astrocytes. Deletion of astrocyte water channel aquaporin-4 (AQP4) in mice alters neuroexcitation by reducing ECS [K(+)] accumulation and slowing K(+) reuptake. These effects could...
Autores principales: | Jin, Byung-Ju, Zhang, Hua, Binder, Devin K., Verkman, A.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536523/ https://www.ncbi.nlm.nih.gov/pubmed/23277478 http://dx.doi.org/10.1085/jgp.201210883 |
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