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Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature

Dynamic force generation in cardiac muscle, which determines cardiac pumping activity, depends on both the number of sarcomeric cross-bridges and on their cycling kinetics. The Frank–Starling mechanism dictates that cardiac force development increases with increasing cardiac muscle length (correspon...

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Detalles Bibliográficos
Autores principales: Milani-Nejad, Nima, Xu, Ying, Davis, Jonathan P., Campbell, Kenneth S., Janssen, Paul M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536524/
https://www.ncbi.nlm.nih.gov/pubmed/23277479
http://dx.doi.org/10.1085/jgp.201210894