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Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature
Dynamic force generation in cardiac muscle, which determines cardiac pumping activity, depends on both the number of sarcomeric cross-bridges and on their cycling kinetics. The Frank–Starling mechanism dictates that cardiac force development increases with increasing cardiac muscle length (correspon...
Autores principales: | Milani-Nejad, Nima, Xu, Ying, Davis, Jonathan P., Campbell, Kenneth S., Janssen, Paul M.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536524/ https://www.ncbi.nlm.nih.gov/pubmed/23277479 http://dx.doi.org/10.1085/jgp.201210894 |
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