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A linkage analysis toolkit for studying allosteric networks in ion channels

A thermodynamic approach to studying allosterically regulated ion channels such as the large-conductance voltage- and Ca(2+)-dependent (BK) channel is presented, drawing from principles originally introduced to describe linkage phenomena in hemoglobin. In this paper, linkage between a principal chan...

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Detalles Bibliográficos
Autor principal: Sigg, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536525/
https://www.ncbi.nlm.nih.gov/pubmed/23250867
http://dx.doi.org/10.1085/jgp.201210859