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A linkage analysis toolkit for studying allosteric networks in ion channels
A thermodynamic approach to studying allosterically regulated ion channels such as the large-conductance voltage- and Ca(2+)-dependent (BK) channel is presented, drawing from principles originally introduced to describe linkage phenomena in hemoglobin. In this paper, linkage between a principal chan...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536525/ https://www.ncbi.nlm.nih.gov/pubmed/23250867 http://dx.doi.org/10.1085/jgp.201210859 |