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Adding Protein Context to the Human Protein-Protein Interaction Network to Reveal Meaningful Interactions

Interactions of proteins regulate signaling, catalysis, gene expression and many other cellular functions. Therefore, characterizing the entire human interactome is a key effort in current proteomics research. This challenge is complicated by the dynamic nature of protein-protein interactions (PPIs)...

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Detalles Bibliográficos
Autores principales: Schaefer, Martin H., Lopes, Tiago J. S., Mah, Nancy, Shoemaker, Jason E., Matsuoka, Yukiko, Fontaine, Jean-Fred, Louis-Jeune, Caroline, Eisfeld, Amie J., Neumann, Gabriele, Perez-Iratxeta, Carol, Kawaoka, Yoshihiro, Kitano, Hiroaki, Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536619/
https://www.ncbi.nlm.nih.gov/pubmed/23300433
http://dx.doi.org/10.1371/journal.pcbi.1002860