Single-Stranded Annealing Induced by Re-Initiation of Replication Origins Provides a Novel and Efficient Mechanism for Generating Copy Number Expansion via Non-Allelic Homologous Recombination

Copy number expansions such as amplifications and duplications contribute to human phenotypic variation, promote molecular diversification during evolution, and drive the initiation and/or progression of various cancers. The mechanisms underlying these copy number changes are still incompletely unde...

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Detalles Bibliográficos
Autores principales: Finn, Kenneth J., Li, Joachim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536649/
https://www.ncbi.nlm.nih.gov/pubmed/23300490
http://dx.doi.org/10.1371/journal.pgen.1003192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536649/
https://www.ncbi.nlm.nih.gov/pubmed/23300490
http://dx.doi.org/10.1371/journal.pgen.1003192

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