Insulin and IGF1 Receptors Are Essential for XX and XY Gonadal Differentiation and Adrenal Development in Mice

Mouse sex determination provides an attractive model to study how regulatory genetic networks and signaling pathways control cell specification and cell fate decisions. This study characterizes in detail the essential role played by the insulin receptor (INSR) and the IGF type I receptor (IGF1R) in...

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Detalles Bibliográficos
Autores principales: Pitetti, Jean-Luc, Calvel, Pierre, Romero, Yannick, Conne, Béatrice, Truong, Vy, Papaioannou, Marilena D., Schaad, Olivier, Docquier, Mylène, Herrera, Pedro Luis, Wilhelm, Dagmar, Nef, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536656/
https://www.ncbi.nlm.nih.gov/pubmed/23300479
http://dx.doi.org/10.1371/journal.pgen.1003160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536656/
https://www.ncbi.nlm.nih.gov/pubmed/23300479
http://dx.doi.org/10.1371/journal.pgen.1003160

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