Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs

Vaccine candidates for HIV-1 so far have not been able to elicit broadly neutralizing antibodies (bNAbs) although they express the epitopes recognized by bNAbs to the HIV envelope glycoprotein (Env). To understand whether and how Env immunogens interact with the predicted germline versions of known...

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Detalles Bibliográficos
Autores principales: Hoot, Sam, McGuire, Andrew T., Cohen, Kristen W., Strong, Roland K., Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F., Sather, D. Noah, Burton, Dennis R., Stamatatos, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536657/
https://www.ncbi.nlm.nih.gov/pubmed/23300456
http://dx.doi.org/10.1371/journal.ppat.1003106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536657/
https://www.ncbi.nlm.nih.gov/pubmed/23300456
http://dx.doi.org/10.1371/journal.ppat.1003106

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