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Starvation, Together with the SOS Response, Mediates High Biofilm-Specific Tolerance to the Fluoroquinolone Ofloxacin

High levels of antibiotic tolerance are a hallmark of bacterial biofilms. In contrast to well-characterized inherited antibiotic resistance, molecular mechanisms leading to reversible and transient antibiotic tolerance displayed by biofilm bacteria are still poorly understood. The physiological hete...

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Detalles Bibliográficos
Autores principales: Bernier, Steve P., Lebeaux, David, DeFrancesco, Alicia S., Valomon, Amandine, Soubigou, Guillaume, Coppée, Jean-Yves, Ghigo, Jean-Marc, Beloin, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536669/
https://www.ncbi.nlm.nih.gov/pubmed/23300476
http://dx.doi.org/10.1371/journal.pgen.1003144