Three-dimensional quantitative structure activity relationship (QSAR) of cytotoxic active 3,5-diaryl-4,5-dihydropyrazole analogs: a comparative molecular field analysis (CoMFA) revisited study

In vitro antitumor evaluation of the synthesized 46 compounds of 3,5-diaryl-4,5-dihydropyrazoles against EAC cell lines and 3D QSAR study using pharmacophore and Comparative Molecular Field Analysis (CoMFA) methods were described. CoMFA derived QSAR model shows a good conventional squared correlatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamad Elgazwy, Abdel-Sattar S, Soliman, DaliaH S, Atta-Allah, Saad R, Ibrahim, Diaa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536690/
https://www.ncbi.nlm.nih.gov/pubmed/22647291
http://dx.doi.org/10.1186/1752-153X-6-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536690/
https://www.ncbi.nlm.nih.gov/pubmed/22647291
http://dx.doi.org/10.1186/1752-153X-6-50

Ejemplares similares