Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction

Cyanide-resistant non-phosphorylating respiration is known in mitochondria from plants, fungi, and microorganisms but is absent in mammals. It results from the activity of an alternative oxidase (AOX) that conveys electrons directly from the respiratory chain (RC) ubiquinol pool to oxygen. AOX thus...

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Detalles Bibliográficos
Autores principales: El-Khoury, Riyad, Dufour, Eric, Rak, Malgorzata, Ramanantsoa, Nelina, Grandchamp, Nicolas, Csaba, Zsolt, Duvillié, Bertrand, Bénit, Paule, Gallego, Jorge, Gressens, Pierre, Sarkis, Chamsy, Jacobs, Howard T., Rustin, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536694/
https://www.ncbi.nlm.nih.gov/pubmed/23300486
http://dx.doi.org/10.1371/journal.pgen.1003182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536694/
https://www.ncbi.nlm.nih.gov/pubmed/23300486
http://dx.doi.org/10.1371/journal.pgen.1003182

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