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The Telomere Capping Complex CST Has an Unusual Stoichiometry, Makes Multipartite Interaction with G-Tails, and Unfolds Higher-Order G-Tail Structures

The telomere-ending binding protein complex CST (Cdc13-Stn1-Ten1) mediates critical functions in both telomere protection and replication. We devised a co-expression and affinity purification strategy for isolating large quantities of the complete Candida glabrata CST complex. The complex was found...

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Detalles Bibliográficos
Autores principales: Lue, Neal F., Zhou, Ruobo, Chico, Lidia, Mao, Ninghui, Steinberg-Neifach, Olga, Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536697/
https://www.ncbi.nlm.nih.gov/pubmed/23300477
http://dx.doi.org/10.1371/journal.pgen.1003145