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Hypothermia Protects the Brain from Transient Global Ischemia/Reperfusion by Attenuating Endoplasmic Reticulum Response-Induced Apoptosis through CHOP

Endoplasmic reticulum (ER) stress has been implicated in the pathology of cerebral ischemia. Apoptotic cell death occurs during prolonged period of stress or when the adaptive response fails. Hypothermia blocked the TNF or Fas-mediated extrinsic apoptosis pathway and the mitochondria pathway of apop...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojie, Wang, Mingshan, Chen, Huailong, Guo, Yunliang, Ma, Fuguo, Shi, Fei, Bi, Yanlin, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536702/
https://www.ncbi.nlm.nih.gov/pubmed/23301071
http://dx.doi.org/10.1371/journal.pone.0053431