Murine CD4(+)CD25(-) cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo

BACKGROUND: Induced regulatory T (iTreg) lymphocytes show promise for application in the treatment of allergic, autoimmune and inflammatory disorders. iTreg cells demonstrate advantages over natural Treg (nTreg) cells in terms of increased number of starting population and greater potential to proli...

Descripción completa

Detalles Bibliográficos
Autores principales: Majowicz, Anna, van der Marel, Sander, te Velde, Anje A, Meijer, Sybren L, Petry, Harald, van Deventer, Sander J, Ferreira, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536706/
https://www.ncbi.nlm.nih.gov/pubmed/23198878
http://dx.doi.org/10.1186/1471-230X-12-172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536706/
https://www.ncbi.nlm.nih.gov/pubmed/23198878
http://dx.doi.org/10.1186/1471-230X-12-172

Ejemplares similares