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RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse

Mechanisms involved with degeneration of motor neurons in amyotrophic lateral sclerosis (ALS; Lou Gehrig's Disease) are poorly understood, but genetically inherited forms, comprising ∼10% of the cases, are potentially informative. Recent observations that several inherited forms of ALS involve...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Urmi, Cotney, Justin, Nagy, Maria, Oh, Sunghee, Leng, Jing, Mahajan, Milind, Mane, Shrikant, Fenton, Wayne A., Noonan, James P., Horwich, Arthur L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536741/
https://www.ncbi.nlm.nih.gov/pubmed/23301088
http://dx.doi.org/10.1371/journal.pone.0053575