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SOX4 Mediates TGF-β-Induced Expression of Mesenchymal Markers during Mammary Cell Epithelial to Mesenchymal Transition

The epithelial to mensenchymal transition program regulates various aspects of embryonic development and tissue homeostasis, but aberrant activation of this pathway in cancer contributes to tumor progression and metastasis. TGF-β potently induces an epithelial to mensenchymal transition in cancers o...

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Detalles Bibliográficos
Autores principales: Vervoort, Stephin J., Lourenço, Ana Rita, van Boxtel, Ruben, Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536747/
https://www.ncbi.nlm.nih.gov/pubmed/23301048
http://dx.doi.org/10.1371/journal.pone.0053238