NOS Inhibition Enhances Myogenic Tone by Increasing Rho-Kinase Mediated Ca(2+) Sensitivity in the Male but Not the Female Gerbil Spiral Modiolar Artery

Cochlear blood flow regulation is important to prevent hearing loss caused by ischemia and oxidative stress. Cochlear blood supply is provided by the spiral modiolar artery (SMA). The myogenic tone of the SMA is enhanced by the nitric oxide synthase (NOS) blocker L-N(G)-Nitro-Arginine (LNNA) in male...

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Detalles Bibliográficos
Autores principales: Reimann, Katrin, Krishnamoorthy, Gayathri, Wangemann, Philine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536759/
https://www.ncbi.nlm.nih.gov/pubmed/23301097
http://dx.doi.org/10.1371/journal.pone.0053655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536759/
https://www.ncbi.nlm.nih.gov/pubmed/23301097
http://dx.doi.org/10.1371/journal.pone.0053655

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