Cargando…

Quinacrine Impairs Enterovirus 71 RNA Replication by Preventing Binding of Polypyrimidine-Tract Binding Protein with Internal Ribosome Entry Sites

Since the 1980s, epidemics of enterovirus 71 (EV71) and other enteroviruses have occurred in Asian countries and regions, causing a wide range of human diseases. No effective therapy is available for the treatment of these infections. Internal ribosome entry sites (IRESs) are indispensable for the i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jianmin, Du, Jiang, Wu, Zhiqiang, Jin, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536785/
https://www.ncbi.nlm.nih.gov/pubmed/23301007
http://dx.doi.org/10.1371/journal.pone.0052954