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An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-κB Activation for Disease-Inducible Gene Transfer

Stimulation of resident cells by NF-κB activating cytokines is a central element of inflammatory and degenerative disorders of the central nervous system (CNS). This disease-mediated NF-κB activation could be used to drive transgene expression selectively in affected cells, using adeno-associated vi...

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Detalles Bibliográficos
Autores principales: Chtarto, Abdelwahed, Bockstael, Olivier, Gebara, Elias, Vermoesen, Katia, Melas, Catherine, Pythoud, Catherine, Levivier, Marc, De Witte, Olivier, Luthi-Carter, Ruth, Clinkers, Ralph, Tenenbaum, Liliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536800/
https://www.ncbi.nlm.nih.gov/pubmed/23301037
http://dx.doi.org/10.1371/journal.pone.0053156