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Catheter-Based Intramyocardial Delivery (NavX) of Adenovirus Achieves Safe and Accurate Gene Transfer in Pigs

BACKGROUND: Hepatocyte growth factor (HGF) is one of the major angiogenic factors being studied for the treatment of ischemic heart diseases. Our previous study demonstrated adenovirus-HGF was effective in myocardial ischemia models. The first clinical safety study showed a positive effect in patien...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Tao, Zhengxian, Zhao, Yingming, Chen, Hongwu, Yong, Yonghong, Liu, Xiang, Wang, Hua, Wu, Zuze, Yang, Zhijian, Yuan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536803/
https://www.ncbi.nlm.nih.gov/pubmed/23301013
http://dx.doi.org/10.1371/journal.pone.0053007