TGF-ß1 Enhances the BMP-2-Induced Chondrogenesis of Bovine Synovial Explants and Arrests Downstream Differentiation at an Early Stage of Hypertrophy

BACKGROUND: Synovial explants furnish an in-situ population of mesenchymal stem cells for the repair of articular cartilage. Although bone morphogenetic protein 2 (BMP-2) induces the chondrogenesis of bovine synovial explants, the cartilage formed is neither homogeneously distributed nor of an exclu...

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Detalles Bibliográficos
Autores principales: Shintani, Nahoko, Siebenrock, Klaus A., Hunziker, Ernst B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536810/
https://www.ncbi.nlm.nih.gov/pubmed/23301025
http://dx.doi.org/10.1371/journal.pone.0053086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536810/
https://www.ncbi.nlm.nih.gov/pubmed/23301025
http://dx.doi.org/10.1371/journal.pone.0053086

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