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TGF-ß1 Enhances the BMP-2-Induced Chondrogenesis of Bovine Synovial Explants and Arrests Downstream Differentiation at an Early Stage of Hypertrophy

BACKGROUND: Synovial explants furnish an in-situ population of mesenchymal stem cells for the repair of articular cartilage. Although bone morphogenetic protein 2 (BMP-2) induces the chondrogenesis of bovine synovial explants, the cartilage formed is neither homogeneously distributed nor of an exclu...

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Detalles Bibliográficos
Autores principales:	Shintani, Nahoko, Siebenrock, Klaus A., Hunziker, Ernst B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536810/ https://www.ncbi.nlm.nih.gov/pubmed/23301025 http://dx.doi.org/10.1371/journal.pone.0053086

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