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Restriction of intestinal stem cell expansion and the regenerative response by YAP

A remarkable feature of regenerative processes is their ability to halt proliferation once an organ’s structure has been restored. The Wnt signaling pathway is the major driving force for homeostatic self-renewal and regeneration in the mammalian intestine. The mechanisms that counterbalance Wnt-dri...

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Detalles Bibliográficos
Autores principales: Barry, Evan R., Morikawa, Teppei, Butler, Brian L., Shrestha, Kriti, de la Rosa, Rosemarie, Yan, Kelley S., Fuchs, Charles S., Magness, Scott T., Smits, Ron, Ogino, Shuji, Kuo, Calvin J., Camargo, Fernando D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536889/
https://www.ncbi.nlm.nih.gov/pubmed/23178811
http://dx.doi.org/10.1038/nature11693