DNA Repair Scaffolds Dampen Checkpoint Signaling by Counteracting the Rad9 Adaptor

In response to genotoxic stress, a transient arrest in cell cycle progression enforced by the DNA damage checkpoint (DDC) signaling pathway positively contributes to genome maintenance(1). Because hyperactivated DDC can lead to a persistent and detrimental cell cycle arrest(2,3), cells must tightly...

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Detalles Bibliográficos
Autores principales: Ohouo, Patrice Y., Bastos de Oliveira, Francisco M., Liu, Yi, Ma, Chu Jian, Smolka, Marcus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536934/
https://www.ncbi.nlm.nih.gov/pubmed/23160493
http://dx.doi.org/10.1038/nature11658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536934/
https://www.ncbi.nlm.nih.gov/pubmed/23160493
http://dx.doi.org/10.1038/nature11658

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