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Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes

AIMS/HYPOTHESIS: Pancreatic islet transplantation (PIT) offers a physiological treatment for type 1 diabetes, but the failure of islet engraftment hinders its application. The female hormone 17β-oestradiol (E2) favours islet survival and stimulates angiogenesis, raising the possibility that E2 may e...

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Detalles Bibliográficos
Autores principales: Liu, S., Kilic, G., Meyers, M. S., Navarro, G., Wang, Y., Oberholzer, J., Mauvais-Jarvis, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536964/
https://www.ncbi.nlm.nih.gov/pubmed/23132340
http://dx.doi.org/10.1007/s00125-012-2764-1